Biomaterials
Research Applications

At the heart of mechanical testing lies biomaterials research applications for soft, natural, and engineered tissue testing. This page lists applications related to soft tissue mechanics, cell mechanics, and mechanobiology.

Biomaterials research applications are organized below by scientific field, with dedicated pages covering specific application areas and testing approaches.

Tissue Engineering and Soft Tissue Biomechanics

These tissue mechanics applications focus on understanding the mechanical behaviour of biological tissues and engineered constructs.

Cardiac Tissue Engineering & Mechanics

Vascular Tissue Engineering & Mechanics

Heart Valve Tissue Engineering & Mechanics

Tendon and Ligament Tissue Engineering & Mechanics

Cartilage & Meniscus Mechanics

Bone Tissue Engineering & Mechanics

Dental & Oral Tissue Biomechanics

Intervertebral Disc Biomechanics

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Skin and Wound Healing Biomechanics

Musculoskeletal Tissue Engineering & Mechanics

Skeletal Muscle & Volumetric Muscle Loss

Ophthalmic Biomechanics & Corneal Tissue Engineering

Peripheral Nerve Regeneration & PNS Mechanics

Lung and Pleural Tissue Biomechanics

Pelvic Floor and Gynecological Biomechanics

Reproductive and Fetal Membrane Mechanics

Gastrointestinal and Urinary Tract Biomechanics

Biomaterials and Advanced Materials

These applications cover materials used in regenerative medicine, cell mechanics, wearable systems, and engineered devices.

Hydrogel Mechanical Testing

Cell Laden Hydrogels

3D Bioprinting & Bioink Materials Testing

Adhesives and Sealants Testing

Polymers and Elastomers Testing

Scaffold Mechanical Testing

Material Fatigue and Durability

Membranes & Thin Films Mechanics

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Soft Robotics Materials

Stimuli Responsive Hydrogels Characterization

ECM & Decellularized Matrix Mechanics

Electroactive and Photothermal Polymers

Injectable & Regenerative Biomaterials

Mechanobiology and Bioelectronics

These mechanobiology applications investigate how mechanical cues influence tissue mechanics, cell mechanics, microtissues, and integrated material systems.

Microtissue & Spheroid Mechanics

Mechanotransduction

Cancer Mechanobiology

Organoid & Tissue Mimetic Systems

Organ-On-A-Chip Systems

Wearable Bioelectronics

Fibrosis & Tissue Remodeling

Stem Cell Mechanobiology

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Drug Screening & Drug Delivery Mechanics

Neural Tissue & CNS Mechanics

Recent Publications

Biomechanical Remodeling of Ascending Aortic Aneurysms Across the 5-cm Surgical Threshold

Ghadie N, Labrosse M, Boodhwani M

JTCVS Open

BioTester

Biaxial Testing

Vascular Tissue Engineering & Mechanics

2026

Bioprinting of a human neuron model for quantifying pollutant toxicity

Yao E, Chen S, Lu G, Sun C, Nguyen QT

International Journal of Bioprinting

MicroTester

Compression TestingMicro-Mechanical Testing

3D Bioprinting & Bioink Materials TestingHydrogel Mechanical TestingNeural Tissue & CNS MechanicsOrganoid and Tissue Mimetic Systems

2026

Inflammation-Responsive baicalin-delivering glycocalyx-mimetic hydrogel-functionalized bioprosthetic valve for antithrombosis and immunomodulation

Chen L, Feng Y, Huang X, et al.

Acta Biomaterialia

BioTester

Tensile Testing

Drug Screening & Drug Delivery MechanicsECM & Decellularized Matrix MechanicsHeart Valve Tissue Engineering & MechanicsHydrogel Mechanical TestingStimuli Responsive Hydrogels Characterization

2026

Application-Focused Case Studies

In collaboration with research institutions across North America, Europe, and Asia, CellScale has developed custom mechanical testing approaches, specialized fixtures, and engineered testing systems to address specific biomaterials research applications challenges.