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Mechanical Testing of Soft Tissues and Biomaterials Blog

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CellScale’s blog shares insights from real-world biomaterials research, mechanical education resources, and product development focused on the mechanical testing of soft tissues.

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UniVert performing hydrated tensile testing on a glowing hydrogel optical fibre mounted between grips in a fluid bath.

July 16, 2026

Hydrogel Optical Fiber Testing Under Repeated Strain

Bioprinted meniscus tissue engineering construct with curved collagen-like alignment patterns in the foreground and a softly blurred CellScale BioTester in the background.

July 2, 2026

Meniscus Tissue Engineering with Boundary-Guided Collagen Alignment

Hydrogel fiber mechanical testing setup showing a thin hydrated fibre suspended across two supports while a small MicroTester beam presses downward in the centre, before and after.

June 25, 2026

Hydrogel Fibre Mechanical Testing of Recombinant Hagfish Protein Materials

MSC spheroids embedded in a translucent PEG-fibrin hydrogel within soft vocal fold-like tissue, with a blurred CellScale MicroTester in the background.

June 11, 2026

Vocal Fold Regeneration with MSC Spheroids

Hydrogel eye drop on a corneal surface with a mechanical testing probe and force-distance curve representing mucoadhesion testing for ocular drug delivery.

May 28, 2026

Mucoadhesion Testing of Hydrogel Eye Drops for Ocular Drug Delivery

May 14, 2026

Flexible Flow Sensor Testing for Pioneering Autonomous Robotics

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A 3D-bioprinted osteosarcoma model

Research Highlights

Peer-reviewed research and application-driven studies featuring CellScale instruments. Here you will find posts related to mechanical testing of soft tissues, mechanical properties of hydrogels, tensile testing of soft biomaterials, compression modulus measurement for gels, and more.

A force-displacement curve on test data on the UniVert

Educational Resources

Evergreen educational content for classroom and training courses, explaining how to test biomaterials mechanically, experimental setup guidance, mechanical testing method explainers, and more.

The MicroTester G2 model

Product & Resource Updates

Announcements and technical updates related to CellScale products and tools. Product releases and upgrades, software and accessory updates, and new technical resources and documentation.

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Company News & Events

Updates from CellScale and the global research community, including conference participation, events, webinars, and company announcements and milestones.

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The Tools Behind the Research

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CellScale instruments support precise mechanical testing and controlled mechanical stimulation of soft tissues, biomaterials, and cell-seeded constructs across a wide range of research applications.

A cartilage sample being compressed on the UniVert

UniVert

Versatile benchtop mechanical tester for tension, compression, pressure, peel, shear, torsion, and more testing of soft tissues and biomaterials.

The BioTester 5000 setup with BioRakes

BioTester

Biaxial mechanical testing of planar tissues, membranes, and engineered constructs in physiologically relevant loading modes.

The MicroTester G2 mechanical tester

MicroTester

Micro-scale mechanical testing of soft tissues, fibers, and micro-mechanical biomaterials where high sensitivity and precision are required.

A top-down view of the 6-Well model of the MechanoCulture T6

MechanoCulture T6

Uniaxial tensile testing of soft biomaterials and 3D cell-seeded matrices in a sterile fluid environment, enabling cyclic or static stretch protocols during culture.

The MechanoCulture J1 bioreactor, viewed from the front with samples mounted in grips

MechanoCulture J1

Multi-sample uniaxial tensile stimulation system with integrated load cells, enabling parallel force- or displacement-controlled stretching of cells and tissues in culture.

A front-right view of the MCTX bioreactor

MechanoCulture TX

Multi-well uniaxial compression stimulation system for cell-seeded constructs and biomaterials, supporting programmable cyclic or static compressive loading.

MCTR bioreactor view from the side

MechanoCulture TR

High-throughput hydrostatic pressure stimulation system with independent wells, enabling cyclic or static pressurization of cultured samples.

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Read the Science

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Read overviews of peer-reviewed publications featuring CellScale systems.

Tailorable Hydrogel Fibers from High-Yield Recombinant Hagfish Intermediate Filament Proteins: A New Frontier in Biomimetic Materials

Bell BE, Wasserman O, et al.

ACS Omega

MicroTester

Flexural and Bending TestingHydrated and Temperature Controlled TestingMicro-Mechanical Testing

Hydrogel Mechanical TestingMembranes and Thin Films Mechanics

2026

SPHERpower: MSC spheroid-based bioequivalent lead to the efficient restoration of the scarred vocal folds

Shpichka A, Svistushkin M, et al.

Stem Cell Research & Therapy

MicroTester

Indentation TestingMicro-Mechanical Testing

Fibrosis & Tissue RemodelingStem Cell Mechanobiology

2026

Formation of assembloids by DNA-mediated synthetic cell self-assembly

Burgstaller A, Lopez Lopez EA, et al.

Soft Matter

MicroTester

Compression TestingMicro-Mechanical Testing

Microtissue and Spheroid MechanicsOrganoid and Tissue Mimetic Systems

2026

MCC950-loaded silk microgel-hydrogel composite scaffolds effectively modulate inflammation for improving tissue interaction and remodeling

Lau K, Grant A, et al.

Acta Biomaterialia

UniVert

Compression Testing

Fibrosis & Tissue RemodelingHydrogel Mechanical TestingInjectable & Regenerative BiomaterialsScaffold Mechanical Testing

2026

3D fractal topography attenuates inflammation and confers resilience to glomerular podocytes

Wang Y, Dikyol C, et al.

Cell Biomaterials

MicroTester

Hydrated and Temperature Controlled TestingIndentation TestingMicro-Mechanical Testing

Fibrosis & Tissue RemodelingMechanotransductionOrganoid and Tissue Mimetic Systems

2026

Advance Your Biomaterials Research

CellScale mechanical testers and bioreactors are trusted by researchers worldwide to deliver accurate, reproducible mechanical testing of soft tissues and engineered biomaterials.

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