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Mechanical Testing of Soft Tissues and Biomaterials Blog

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CellScale’s blog shares insights from real-world biomaterials research, mechanical education resources, and product development focused on the mechanical testing of soft tissues.

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Mechanical loading of a vascularized bone organoid under compression with the MechanoCulture TX in the background.

August 25, 2026

Mechanical Loading of Bone Organoids Under Estrogen Deficiency

CellScale MicroTester in the background behind transparent hydrogel microbeads on a lab bench, with a foreground microbead showing green bacterial colonies to illustrate hydrogel stiffness and bacterial growth.

August 18, 2026

Hydrogel Stiffness and Bacterial Growth in Gut Microbiota Culture

Soy protein microcarriers for cultivated meat with bovine muscle cells, including one particle undergoing parallel-plate compression testing.

August 10, 2026

Testing Soy Protein Microcarriers for Cultivated Meat Cell Expansion

UniVert hydrogel tensile testing setup with camera imaging and a digital image correlation strain map showing localized deformation.

July 30, 2026

Hydrogel Tensile Testing Reveals Strain Localization in Architected Materials

An aortic tissue sample being biaxially tested with BioRakes on the BioTester for vascular tissue engineering research

July 23, 2026

Carotid Artery Biaxial Testing with Axial Pre-Stretch

UniVert performing hydrated tensile testing on a glowing hydrogel optical fibre mounted between grips in a fluid bath.

July 16, 2026

Hydrogel Optical Fiber Testing Under Repeated Strain

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A 3D-bioprinted osteosarcoma model

Research Highlights

Peer-reviewed research and application-driven studies featuring CellScale instruments. Here you will find posts related to mechanical testing of soft tissues, mechanical properties of hydrogels, tensile testing of soft biomaterials, compression modulus measurement for gels, and more.

A force-displacement curve on test data on the UniVert

Educational Resources

Evergreen educational content for classroom and training courses, explaining how to test biomaterials mechanically, experimental setup guidance, mechanical testing method explainers, and more.

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Product & Resource Updates

Announcements and technical updates related to CellScale products and tools. Product releases and upgrades, software and accessory updates, and new technical resources and documentation.

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Company News & Events

Updates from CellScale and the global research community, including conference participation, events, webinars, and company announcements and milestones.

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The Tools Behind the Research

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CellScale instruments support precise mechanical testing and controlled mechanical stimulation of soft tissues, biomaterials, and cell-seeded constructs across a wide range of research applications.

A cartilage sample being compressed on the UniVert

UniVert

Versatile benchtop mechanical tester for tension, compression, pressure, peel, shear, torsion, and more testing of soft tissues and biomaterials.

The BioTester 5000 setup with BioRakes

BioTester

Biaxial mechanical testing of planar tissues, membranes, and engineered constructs in physiologically relevant loading modes.

The MicroTester G2 mechanical tester

MicroTester

Micro-scale mechanical testing of soft tissues, fibers, and micro-mechanical biomaterials where high sensitivity and precision are required.

A top-down view of the 6-Well model of the MechanoCulture T6

MechanoCulture T6

Uniaxial tensile testing of soft biomaterials and 3D cell-seeded matrices in a sterile fluid environment, enabling cyclic or static stretch protocols during culture.

The MechanoCulture J1 bioreactor, viewed from the front with samples mounted in grips

MechanoCulture J1

Multi-sample uniaxial tensile stimulation system with integrated load cells, enabling parallel force- or displacement-controlled stretching of cells and tissues in culture.

A front-right view of the MCTX bioreactor

MechanoCulture TX

Multi-well uniaxial compression stimulation system for cell-seeded constructs and biomaterials, supporting programmable cyclic or static compressive loading.

MCTR bioreactor view from the side

MechanoCulture TR

High-throughput hydrostatic pressure stimulation system with independent wells, enabling cyclic or static pressurization of cultured samples.

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Read the Science

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Read overviews of peer-reviewed publications featuring CellScale systems.

Hydrophilic Polydopamine (hPDA) Fueled Bioglue Enhances Tissue Adhesion and Promotes Healing of Avascular Meniscus Tears

Jani HR, Jeremias MA, et al.

Biomaterials

UniVert

Compression TestingShear TestingTensile Testing

Adhesives and Sealants TestingCartilage and Meniscus MechanicsHydrogel Mechanical TestingInjectable & Regenerative BiomaterialsScaffold Mechanical Testing

2026

Mechanical loading under estrogen deficiency enhances mineralization and osteoblast maturation in an advanced 3D vascularized bone organoid driven by hypertrophy and apoptosis

Bukhari MMM, Naqvi SM, et al.

Journal of Biomechanics

MechanoCulture TX

Compression TestingFatigue TestingHydrated and Temperature Controlled Testing

Bone Tissue Engineering & MechanicsMechanotransductionOrganoid and Tissue Mimetic SystemsStem Cell Mechanobiology

2026

Mycoelectronics: Bioprinted Living Fungal Bioelectronics for Artificial Sensation

Cai X, Ofori-Boateng S, et al.

Proceedings of the National Academy of Sciences (PNAS)

UniVert

Tensile Testing

Cell Laden HydrogelsHydrogel Mechanical TestingSoft Robotics MaterialsWearable Bioelectronics

2026

3D fractal topography attenuates inflammation and confers resilience to glomerular podocytes

Wang Y, Dikyol C, et al.

Cell Biomaterials

MicroTester

Hydrated and Temperature Controlled TestingIndentation TestingMicro-Mechanical Testing

Fibrosis & Tissue RemodelingMechanotransductionOrganoid and Tissue Mimetic Systems

2026

Mechanically graded granular scaffolds for osteochondral tissue engineering

Mierswa SC, Wheeler EE, et al.

Biomaterials Advances

MicroTester

Compression TestingHydrated and Temperature Controlled TestingMicro-Mechanical Testing

Bone Tissue Engineering & MechanicsCartilage and Meniscus MechanicsScaffold Mechanical Testing

2026

Advance Your Biomaterials Research

CellScale mechanical testers and bioreactors are trusted by researchers worldwide to deliver accurate, reproducible mechanical testing of soft tissues and engineered biomaterials.

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