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Mechanical test systems

At CellScale, our test systems are optimized from the ground up to characterize the mechanical properties of biomaterials. Environmental chambers and imaging are integral system functions, not afterthoughts. For needs ranging from micro-scale compression to biaxial tension, trust CellScale’s systems to provide cutting edge data. Our products are:

BioTester – planar biaxial testing

MicroTester – micro-scale mechanical testing

UniVert – tension, compression and bending testing

UStretch – precision tension testing


CellScale’s bioreactors provide insights into the response of cells and tissues to mechanical stimulation.  We have systems optimized for high-throughput, real-time imaging, 3D scaffold use, and multi-modal stimulation. CellScale also has extensive experience in developing custom solutions that exceed expectations. The Cell-Stimulation products are:

MCB1  – biaxial stimulation of cell monolayers and 3D constructs

MCFX – uniaxial stimulation of cell monolayers with imaging

MCT6 – high-force uniaxial stimulation of 3D constructs

We have bought multiple CellScale products and are extremely happy with all of them.  The BioTester is by far the best-designed, easiest-to-use biaxial testing system I have used in my career. The MechanoCulture B1 provides great control over mechanical stretch protocols and is the only system we have found that readily accommodates cell-populated gels. Finally, the MechanoCulture FX is a great system for mechanobiology experiments. Across all of these products, CellScale has worked with us to help us find the right product, and when needed even to adapt their devices for our experiments. I can’t recommend the products and the company highly enough. Prof. Jeff Holmes

University of Virginia

CellScale’s innovative biomechanical testing equipment, including the MicroTester and a customized UniVert system, has greatly enabled our research, allowing us to accurately characterize the properties of a diverse range of engineered bioscaffolds under physiological conditions. The systems are robust and easy to use, and offer flexibility in the types of biomaterials and tissues that can be tested. What truly sets CellScale apart, is their commitment to Customer Service – they have gone above and beyond to help us in getting the most from our data and are always very prompt and helpful in responding to our questions.

Lauren Flynn, Ph.D., P.Eng
Western University

Interview with Peter Hammer at the Boston Children’s Hospital

CellScale interviews Dr. Peter Hammer from the Boston Children’s Hospital about his unique role as an engineer at the hospital working directly with the cardiac surgeons, and his work with the BioTester.

CellScale FitBit Giveaway

We are giving away a new FitBit Ionic watch to our customers! Read more to learn how to win!

CellScale User Publication Highlight: Image-based Analysis of Uniaxial Ring Test

Dr. Kurniawan and his team at Eindhoven University of Technology develops an image-based approach to the common uniaxial ring test for mechanical characterization of soft materials and biological tissues.

CellScale User Publication Highlight: An Engineered Meniscus with Zone-specific Biochemical Composition

Dr Vasif Hasirci and his team at the Middle East Technical University in Turkey has created a 3D printed PCL/hydrogel construct of a meniscus. Read more about the details here, including their dynamic stress test on the constructs.

CellScale User Publication Highlight: Collagenous Bioscaffolds for the Treatment of Cutaneous Wounds

Prof Lauren Flynn at Western University creates a 3D collagenous bioscaffold comprised of DAT and COL bead foams to address the need for a better treatment of chronic or non-healing skin wounds.

Mechanical Testing of Biomaterials for Non-Engineers

Biomaterials research teams often have members from engineering, biology, medicine, and other fields. For non-engineers it can be easy to understand why mechanical properties are important, but testing can seem complex and confusing. Here’s a quick framework to help you get started.

CellScale User Publication Highlight: Anti-fatigue-fracture Hydrogels

German Parada and his team from Zhao Lab at MIT used the UStretch to create hydrogels that can exceed a fatigue threshold of 1000 J/m2.

CellScale User Publication Highlight: A Platform for Generation of Chamber-Specific Cardiac Tissues and Disease Modeling

Yimu Zhao (MASc.) and her team at the University of Toronto developed a unique tissue cultivation and drug testing platform called the “Biowire II”. Find out how the MicroTester played a part in this significant invention!

CellScale User Publication Highlight: Investigating regional variations in the biaxial mechanical properties of heart valve leaflets

Dr Chung-Hao Lee and his cardiovascular biomechanics team in the School of Aerospace and Mechanical Engineering at the University of Oklahoma uses the CellScale BioTester to further research on porcine atrioventricular heart valve leaflets.

CellScale User Publication Highlight: Characterization of single crystalline austenitic stainless steel thin struts processed by laser powder bed fusion

Mr Xianglong Wang from McGill University shares his findings and phenomenon discovery on experimenting with single crystalline austenitic steel struts.