During the COVID-19 pandemic, CellScale is taking steps to protect our employees while continuing to serve our customers. We are working from home whenever possible and minimizing direct contact.

Due to reduced activity in other areas, we have more time than ever for product demonstrations, and application discussions, and other virtual points of contact. Whatever your situation, we are eager to talk with you and offer our advice about your current and future research. Call us at 519-342-6870 or click here to submit a request form to get in touch with a member of our team today!

We hope you’ll take care during this period as we all do our part to get through this together.

Caleb Horst, President – CellScale Biomaterials Testing

Capable systems. Fully supported.

Our systems are up to the task every time. They include the features you need and free lifetime technical support.

CellScale Biomaterials Testing

Capable Systems. Fully Supported.

Specializing in biomaterials testing equipment since 2005

Mechanical Test Systems

At CellScale, our test systems are optimized from the ground up to characterize the mechanical properties of biomaterials. Environmental chambers and imaging are integral system functions, not afterthoughts. For needs ranging from micro-scale compression to biaxial tension, trust CellScale’s systems to provide cutting edge data. Our products are:

BioTester – planar biaxial testing

MicroTester – micro-scale mechanical testing

UniVert – tension, compression and bending testing

UStretch – precision tension testing

Mechano-bioreactors

CellScale’s bioreactors provide insights into the response of cells and tissues to mechanical stimulation.  We have systems optimized for high-throughput, real-time imaging, 3D scaffold use, and multi-modal stimulation. CellScale also has extensive experience in developing custom solutions that exceed expectations. The Cell-Stimulation products are:

MCB1  – biaxial stimulation of cell monolayers and 3D constructs

MCFX – uniaxial stimulation of cell monolayers with imaging

MCT6 – high-force uniaxial stimulation of 3D constructs

MCTR – high-throughput hydrostatic pressure stimulation

MCTX – uniaxial compression stimulation

CellScale introduces the VitroFlo

A microphysiological system that incorporates flow over cells without pumps, tubes or valves. The VitroFlo consists of a wellplate with 12 microfluidic channels and a programmable rocker. 

The system is now available for beta testing. Click here for more information.

I purchased the Cell Scale biaxial device in my first year as an Assistant Professor. It allowed my first graduate student to start collecting data from day one rather than spend the time to design, build, and validate a custom device first.

Assistant Professor Manuel Rausch

The University of Texas at Austin

I have used CellScale both in the classroom and research setting. It was a great tool for teaching undergraduates the principles of mechanical testing with a hands-on, experiential approach. In my laboratory, it enabled us to determine the mechanical properties of a soft biomaterial developed in our lab that could not be measured by other means. It met all our needs, and was easy to use. 

Associate Professor Kathryn Grandfield

McMaster University

CellScale User Publication Highlight: Multiparametric Analysis of Tissue Spheroids

Dr. Elena Bulanova and her team at the Laboratory for Biotechnological Research 3D Bioprinting Solutions in Russia present their article on fabrication and analysis of tissue spheroids. Their design protocol applies to any cell line and aims to meet high quality standards such as consistent geometry, defined mechanical properties and viability.

CellScale User Publication Highlight: Promoting Maturation of hiPSC-derived Cardiomyocytes with Re-entrant Waves

Dr. Li Liu and her team at the Osaka University Graduate School of Medicine present their breakthrough research to mature hiPSC-derived cardiomyocytes in a self-organized tissue ring. By mimicking the physiology of adult cardiomyocytes, the team’s findings present a viable solution to drug screening and regenerative therapy applications.

CellScale User Publication Highlight: A Wireless Smart Bandage with Miniaturized Needle Arrays

Dr. Ali Tamayol and his team from the University of Nebraska-Lincoln developed a wearable device that can deliver agents to critical layers of the wound bed in a minimally invasive fashion. Read more about their solution to treat chronic wounds suffered by diabetic patients.

CellScale User Publication Highlight: A Low-cost, Pilot-scale, Melt Processing System

Dr. Jon Pokorski and his team from the University of California at San Diego presents a solution to high-cost, bulky and high-material-consuming melt-processing system for academic laboratories. In his study, he demonstrates the dispersion of particles in melt processed polymers produced by their invention.

CellScale User Publication Highlight: The Effect of Cyclic Stretch and Shear Stretch on Inflammation and Tissue Formation

Dr. Carlijn V.C. Bouten and her team at the Eindhoven University of Technology explored into the underlying mechanisms of premature graft failure by creating a human in vitro model of material-driven vascular regeneration. Read on to discover how cyclic stretch and shear stretch respectively affects inflammation and tissue formation.

CellScale User Publication Highlight: Hyperelastic Characterization of Mesh for Abdominal Hernia Repair

Dr. Georgina Carbajal de la Torre and her team from Universidad Michoacana de San Nicolas de Hidalgo in Mexico shares with us her fascinating research into various synthetic mesh for abdominal wall hernia repair. By understanding the mechanical properties of these materials, surgical treatments of abdominal hernia can vastly improve thus reducing the hernia recurrence rate for patients.

CellScale User Publication Highlight: New Testing Method for Viscoelasticity of Biomaterials

Ludovica Cacopardo from the University of Pisa under Associate Professor Arti Ahluwalia publishes this article on a new testing method for viscoelasticity through stress-rate measurements and load-control testing. Learn how the MechanoCulture TR played a major role in their discovery.

CellScale User Publication Highlight: Optimization for Accelerated Corneal Crosslinking Procedure

Here is the first customer publication highlight featuring a commercial (non-academic) entity and their research with our equipment! Dr. Desmond Adler and his team from Avedro (now a Glaukos company) investigated on the optimization of oxygen dynamics, UV-A delivery, and drug formulation for Accelerated Epi-On Corneal Crosslinking.

CellScale User Publication Highlight: Methods of Delivering Mechanical Stimuli to OOC

University of Arizona’s Dr. Jeong-Yeol Yoon and his Ph.D. student Kattika Kaarj presents this journal paper on Organ-on-a-chip devices and the mechanical stimuli they can create on human cells and tissues. This excellent summary focuses on the technical details of device design and equipment used, categorizing them under 5 types of mechanical stimuli.

CellScale User Publication Highlight: Effects of Different Constitutive Laws on Fluid-Structure Interaction (FSI) Simulation of the Mitral Valve

Dr. Xiaoyu Luo from the University of Glasgow in collaboration with 3 top scientific universities in China has presented a highly detailed study on the dynamic behavior of mitral valve leaflets and chordae tendineae under physiological conditions.

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