Peel Testing
for Bioadhesives and Soft Materials

Peel testing is used to evaluate the adhesive strength and interfacial mechanics of bonded materials by applying a controlled peeling force. In biomaterials research, peel testing is especially valuable for studying bioadhesives, tissue sealants, hydrogels, and layered soft materials, where failure often occurs at an interface rather than within the bulk material.

The UniVert mechanical tester setup with a peel test fixture and tape being peeled
A UniVert S setup with the Peel Testing fixture

What Peel Testing Measures

Peel testing quantifies the resistance of an adhesive or bonded interface to separation under peeling forces.

The mechanical test provides insight into how bonded materials behave under realistic loading conditions that involve progressive separation rather than uniform tension.

A peel test on red adhesive tape with the UniVert

These measurements form the basis of peel strength testing, where resistance to interfacial separation is quantified under controlled peeling conditions.

The UniVert setup with Peel Fixture and the LabJoy software open

Peel Testing in Biomaterials Research

Peel testing is used in biomaterials and soft tissue research where interfacial adhesion governs performance and failure rather than bulk material strength. This approach is applied in adhesive peel testing to evaluate how bonded interfaces perform under physiologic deformation and removal.

Sample Types Suitable for Peel Testing

How a Peel Test Works

In peel testing, one bonded layer is progressively separated from another while force and displacement are recorded. The resulting force–displacement data are used to quantify peel strength and interfacial adhesion behaviour.

Common configurations include 90-degree and 180-degree peel tests, which control the direction and magnitude of applied forces and influence measured peel strength.

A constant peel rate is applied to ensure steady-state separation and repeatable measurement of peel force.

Peel tests can be performed in fluid or temperature-controlled environments (custom fixtures) to preserve physiologic relevance for hydrogels and biological adhesives. This setup is particularly important for performing a hydrogel peel strength test under physiologically relevant fluid conditions.

Visual inspection and imaging distinguish between adhesive failure at the interface and cohesive failure within the bonded material.

Recommended Instrument for Peel Testing

The CellScale UniVert supports peel testing with precise force control for evaluating interfacial adhesion in bioadhesives and soft materials.

Featured Publications Using Peel Testing

The Biomechanical Properties of Porcine Intervertebral Disc Tissue Treated with Different Fixation Solutions

Chow N, Sinopoli SI, et al.

Journal of the Mechanical Behavior of Biomedical Materials

BioTesterUStretch

Peel TestingTensile Testing

Intervertebral Disc Biomechanics

2026

Tissue-adhesive hydrogel–MXene biosensor for in situ intraoral TNF-α detection

Wong TH, Liu W, et al.

Science Advances

UStretch

Hydrated and Temperature Controlled TestingPeel TestingTensile Testing

Dental & Oral Tissue BiomechanicsHydrogel Mechanical TestingWearable Bioelectronics

2026

An Investigation of the Mechanism of Adjacent Segment Disease in a Porcine Spine Model

Chow N, Sinopoli SI, et al.

Clinical Biomechanics

BioTesterUStretch

Hydrated and Temperature Controlled TestingMicro-Mechanical TestingPeel TestingTensile Testing

Fibrosis & Tissue RemodelingIntervertebral Disc BiomechanicsMechanotransductionMusculoskeletal Tissue Engineering & Mechanics

2025

Ready to Perform Peel Testing?

CellScale provides controlled peel testing solutions for bioadhesives, hydrogels, and soft material interfaces.

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