Researchers in the McDevitt Lab at Georgia Tech study the mechanical properties of embryonic stem cell spheroids to understand how stiffness influences cell differentiation.
In this interview, Rabbia Saeed explains how micro-scale mechanical testing enables characterization of micromass stem cell aggregates that fall between the size limits of atomic force microscopy and traditional uniaxial testing systems. The work includes force–displacement testing, stress relaxation, and creep measurements to capture the viscoelastic behavior of living spheroids.
This research contributed to peer-reviewed publications on the role of mechanical properties in stem cell aggregate function and differentiation.
