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Mechanical Testing of Soft Tissues and Biomaterials Blog

CellScale’s blog shares insights from real-world biomaterials research, mechanical education resources, and product development focused on the mechanical testing of soft tissues.

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Transparent bioreactor chamber holding an aligned electrospun tendon scaffold with elongated cells oriented along the fibre direction, illustrating mechanical stimulation in tendon tissue engineering in a research lab.

April 9, 2026

Mechanical Stimulation in Tendon Tissue Engineering

Featured illustration of a 3D bioprinted osteosarcoma model with tumour spheroids embedded in a trabecular-like hydrogel scaffold

April 2, 2026

New 3D Bioprinted Osteosarcoma Model for Drug Testing

March 26, 2026

Scleral Cross-Linking for Myopia: Biomechanics and Safety Over Time

Injectable scaffolded spheroid at the tip of a needle above intervertebral disc tissue, illustrating nucleus pulposus regeneration with a 3D printed microscaffold-supported cell construct.

March 19, 2026

Nucleus Pulposus Regeneration Using Injectable Scaffolded Spheroids

Featured image of re-endothelialization of decellularized lung scaffolds showing anti-CD31 coating and endothelial lining in a lung vessel

March 12, 2026

Re-endothelialization of Decellularized Lung Scaffolds with Anti-CD31 Preconditioning

MEA contractility assay illustration showing an MEA chip with an engineered heart tissue strip over an electrode grid, with synchronized electrical and contraction force waveforms.

March 5, 2026

MEA Contractility Assay: When MEA Signals Look Fine But Force Doesn’t

Explore Blog Categories

Research Highlights

Peer-reviewed research and application-driven studies featuring CellScale instruments. Here you will find posts related to mechanical testing of soft tissues, mechanical properties of hydrogels, tensile testing of soft biomaterials, compression modulus measurement for gels, and more.

Educational Resources

Evergreen educational content for classroom and training courses, explaining how to test biomaterials mechanically, experimental setup guidance, mechanical testing method explainers, and more.

The MicroTester G2 model

Product & Resource Updates

Announcements and technical updates related to CellScale products and tools. Product releases and upgrades, software and accessory updates, and new technical resources and documentation.

Company News & Events

Updates from CellScale and the global research community, including conference participation, events, webinars, and company announcements and milestones.

The Tools Behind the Research

CellScale instruments support precise mechanical testing and controlled mechanical stimulation of soft tissues, biomaterials, and cell-seeded constructs across a wide range of research applications.

A cartilage sample being compressed on the UniVert

UniVert

Versatile benchtop mechanical tester for tension, compression, pressure, peel, shear, torsion, and more testing of soft tissues and biomaterials.

The BioTester 5000 setup with BioRakes

BioTester

Biaxial mechanical testing of planar tissues, membranes, and engineered constructs in physiologically relevant loading modes.

The MicroTester G2 mechanical tester

MicroTester

Micro-scale mechanical testing of soft tissues, fibers, and micro-mechanical biomaterials where high sensitivity and precision are required.

MechanoCulture T6

Uniaxial tensile testing of soft biomaterials and 3D cell-seeded matrices in a sterile fluid environment, enabling cyclic or static stretch protocols during culture.

The MechanoCulture J1 bioreactor, viewed from the front with samples mounted in grips

MechanoCulture J1

Multi-sample uniaxial tensile stimulation system with integrated load cells, enabling parallel force- or displacement-controlled stretching of cells and tissues in culture.

A front-right view of the MCTX bioreactor

MechanoCulture TX

Multi-well uniaxial compression stimulation system for cell-seeded constructs and biomaterials, supporting programmable cyclic or static compressive loading.

MCTR bioreactor view from the side

MechanoCulture TR

High-throughput hydrostatic pressure stimulation system with independent wells, enabling cyclic or static pressurization of cultured samples.

See the Research Behind the Stories

Read overviews of peer-reviewed publications featuring CellScale systems.

3D fractal topography attenuates inflammation and confers resilience to glomerular podocytes

Wang Y, Dikyol C, et al.

Cell Biomaterials

MicroTester

Hydrated and Temperature Controlled TestingIndentation TestingMicro-Mechanical Testing

Fibrosis & Tissue RemodelingMechanotransductionOrganoid and Tissue Mimetic Systems

2026

Mechanically graded granular scaffolds for osteochondral tissue engineering

Mierswa SC, Wheeler EE, et al.

Biomaterials Advances

MicroTester

Compression TestingHydrated and Temperature Controlled TestingMicro-Mechanical Testing

Bone Tissue Engineering & MechanicsCartilage and Meniscus MechanicsScaffold Mechanical Testing

2026

Postpartum biomechanical adaptations of the anterior abdominal wall in a rat model: Implications for diastasis rectus abdominis

Lax M, Morgan M, et al.

Clinical Biomechanics

BioTester

Tensile Testing

Musculoskeletal Tissue Engineering & MechanicsPelvic Floor and Gynecological Biomechanics

2026

Comparison of Mechanical Properties of Patient-Specific Direct 3D-Printed Aortic Valve for Simulation Trainings: A Comparative Study

Cheheili Sobbi S, Pavlykova-Chertovska A, et al.

Innovations

BioTester

Digital Image Correlation (DIC)Tensile Testing

Cardiac Tissue Engineering & MechanicsHeart Valve Tissue Engineering & MechanicsPolymers and Elastomers Testing

2026

Effect of Sulfated Polysaccharides and Laponite in Composite Porous Scaffolds on Osteogenesis

Karamesouti A, Chatzinikolaidou M

Biomolecules

UniVert

Compression TestingHydrated and Temperature Controlled Testing

Bone Tissue Engineering & MechanicsHydrogel Mechanical TestingScaffold Mechanical Testing

2026

Advance Your Biomaterials Research

CellScale mechanical testers and bioreactors are trusted by researchers worldwide to deliver accurate, reproducible mechanical testing of soft tissues and engineered biomaterials.

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