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Mechanical Testing of Soft Tissues and Biomaterials Blog

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CellScale’s blog shares insights from real-world biomaterials research, mechanical education resources, and product development focused on the mechanical testing of soft tissues.

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Featured illustration of a 3D bioprinted osteosarcoma model with tumour spheroids embedded in a trabecular-like hydrogel scaffold

April 2, 2026

New 3D Bioprinted Osteosarcoma Model for Drug Testing

March 26, 2026

Scleral Cross-Linking for Myopia: Biomechanics and Safety Over Time

Injectable scaffolded spheroid at the tip of a needle above intervertebral disc tissue, illustrating nucleus pulposus regeneration with a 3D printed microscaffold-supported cell construct.

March 19, 2026

Nucleus Pulposus Regeneration Using Injectable Scaffolded Spheroids

Featured image of re-endothelialization of decellularized lung scaffolds showing anti-CD31 coating and endothelial lining in a lung vessel

March 12, 2026

Re-endothelialization of Decellularized Lung Scaffolds with Anti-CD31 Preconditioning

MEA contractility assay illustration showing an MEA chip with an engineered heart tissue strip over an electrode grid, with synchronized electrical and contraction force waveforms.

March 5, 2026

MEA Contractility Assay: When MEA Signals Look Fine But Force Doesn’t

Isometric cutaway of skin showing a porous 3D printed ECM hydrogel graft seated in a wound cavity with embedded microsensor beads, a pO2 oxygen gradient, and a small compression-testing icon with a stress-strain curve.

February 26, 2026

Oxygen-sensing 3D printed skin grafts: printing psECM and checking stiffness under compression

Explore Blog Categories

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A 3D-bioprinted osteosarcoma model

Research Highlights

Peer-reviewed research and application-driven studies featuring CellScale instruments. Here you will find posts related to mechanical testing of soft tissues, mechanical properties of hydrogels, tensile testing of soft biomaterials, compression modulus measurement for gels, and more.

A force-displacement curve on test data on the UniVert

Educational Resources

Evergreen educational content for classroom and training courses, explaining how to test biomaterials mechanically, experimental setup guidance, mechanical testing method explainers, and more.

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Product & Resource Updates

Announcements and technical updates related to CellScale products and tools. Product releases and upgrades, software and accessory updates, and new technical resources and documentation.

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Company News & Events

Updates from CellScale and the global research community, including conference participation, events, webinars, and company announcements and milestones.

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The Tools Behind the Research

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CellScale instruments support precise mechanical testing and controlled mechanical stimulation of soft tissues, biomaterials, and cell-seeded constructs across a wide range of research applications.

A cartilage sample being compressed on the UniVert

UniVert

Versatile benchtop mechanical tester for tension, compression, pressure, peel, shear, torsion, and more testing of soft tissues and biomaterials.

The BioTester 5000 setup with BioRakes

BioTester

Biaxial mechanical testing of planar tissues, membranes, and engineered constructs in physiologically relevant loading modes.

The MicroTester G2 mechanical tester

MicroTester

Micro-scale mechanical testing of soft tissues, fibers, and micro-mechanical biomaterials where high sensitivity and precision are required.

A top-down view of the 6-Well model of the MechanoCulture T6

MechanoCulture T6

Uniaxial tensile testing of soft biomaterials and 3D cell-seeded matrices in a sterile fluid environment, enabling cyclic or static stretch protocols during culture.

The MechanoCulture J1 bioreactor, viewed from the front with samples mounted in grips

MechanoCulture J1

Multi-sample uniaxial tensile stimulation system with integrated load cells, enabling parallel force- or displacement-controlled stretching of cells and tissues in culture.

A front-right view of the MCTX bioreactor

MechanoCulture TX

Multi-well uniaxial compression stimulation system for cell-seeded constructs and biomaterials, supporting programmable cyclic or static compressive loading.

MCTR bioreactor view from the side

MechanoCulture TR

High-throughput hydrostatic pressure stimulation system with independent wells, enabling cyclic or static pressurization of cultured samples.

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Read the Science

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Read overviews of peer-reviewed publications featuring CellScale systems.

State-Programmable Conductive and Reactivatable Bio-Adhesive for High-Fidelity Epidermal Biointerfaces

Ahmed S, Momin M, et al.

Small

UniVert

Peel TestingTensile Testing

Adhesives and Sealants TestingPolymers and Elastomers TestingWearable Bioelectronics

2026

Semisolid extrusion 3D printing for pharmaceutical compounding: influence of active ingredients on alginate-based inks and tailored-dosage forms properties

Falcone G, Amante C, et al.

Carbohydrate Polymer Technologies and Applications

UniVert

Compression Testing

3D Bioprinting & Bioink Materials TestingDrug Screening & Drug Delivery MechanicsHydrogel Mechanical TestingPolymers and Elastomers Testing

2026

Deep Learning-Based Inclusion Boundary Identification Using Wave Propagation in Optical Coherence Elastography

Zhang G, Liao J, et al.

Journal of Biophotonics

UniVert

Compression Testing

Hydrogel Mechanical TestingSkin and Wound Healing Biomechanics

2026

Flexible 3D-Printed Piezoelectric and Bioinstructive Platforms for Skeletal Muscle Development and Organization

Ozhava D, Sonaye SY, et al.

ACS Applied Materials & Interfaces

UniVert

Compression Testing

3D Bioprinting & Bioink Materials TestingElectroactive and Photothermal PolymersHydrogel Mechanical TestingSkeletal Muscle & Volumetric Muscle LossStimuli Responsive Hydrogels Characterization

2026

Hydrophilic Polydopamine (hPDA) Fueled Bioglue Enhances Tissue Adhesion and Promotes Healing of Avascular Meniscus Tears

Jani HR, Jeremias MA, et al.

Biomaterials

UniVert

Compression TestingShear TestingTensile Testing

Adhesives and Sealants TestingCartilage and Meniscus MechanicsHydrogel Mechanical TestingInjectable & Regenerative BiomaterialsScaffold Mechanical Testing

2026

Advance Your Biomaterials Research

CellScale mechanical testers and bioreactors are trusted by researchers worldwide to deliver accurate, reproducible mechanical testing of soft tissues and engineered biomaterials.

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