Mechanically-Compliant Magnetoelectric Sutures for Wound Management

This study reports the development of a mechanically compliant magnetoelectric (ME) suture designed to integrate wound closure with on-demand, untethered electrical stimulation for accelerated healing. The suture incorporates core–shell magnetoelectric nanoparticles embedded in a piezoelectric polymer matrix, enabling programmable electrical output under external magnetic fields. A polyzwitterionic hydrogel coating improves mechanical compliance, biocompatibility, and reduces foreign body response while facilitating low-friction removal. In a rat incisional wound model, ME sutures subjected to daily magnetic induction significantly accelerated healing, reducing recovery time from ten days to five days. The work establishes a multifunctional suture platform that synergizes adaptive mechanics with electrically augmented tissue repair.