Design of MOF/soja based-resin scaffolds by 3D resin printing technique

This study fabricated hybrid porous scaffolds by stereolithography (SLA) 3D printing using a UV-curable soy-based commercial resin (Anycubic) reinforced with low loadings of the iron-based metal–organic framework MIL-88A (0.01 wt% and 0.03 wt%). MIL-88A was synthesized via a hydrothermal route (FeCl3·6H2O + fumaric acid) and incorporated into resin by high-speed mixing before printing cylindrical porous scaffolds (0.5 mm designed pore size). Composite scaffolds were characterized by FTIR/XRD (confirming MIL-88A formation), SEM/EDS (rod-like MIL-88A morphology and dispersion within printed resin), and in vitro immersion in simulated body fluid (SBF) and PBS to assess bioactivity and biodegradation over 9–28 days. Weight-loss data indicated modest degradation in PBS (~1.4–1.6%) and higher loss in SBF (~2.3–2.5% for control and 0.01 wt%, higher/variable for 0.03 wt%). Overall, MIL-88A inclusion maintained printability and porous architecture while supporting bioactivity/biodegradability profiles consistent with tissue engineering scaffold requirements.