PEER-REVIEWED PUBLICATION

2020

Surface Representation of the Urinary Bladder and Bio-mechanical Analysis by Linear Dynamic Model

Guzman-Diaz K, Alvarado-Gonzalez A, et al.

IFMBE Proceedings

Tecnologico de Monterrey, University of Texas at Dallas

RESEARCH SUMMARY
This conference paper investigated biomechanical characterization of the urinary bladder using both three-dimensional surface reconstruction and tensile testing-based viscoelastic modeling. Three male bovine bladders were scanned to generate digital surface reconstructions with an average point cloud of about 9 × 10^6 elements, and tissue samples from upper, middle, and lower bladder regions were mechanically tested under tensile loading. A linear viscoelastic Voigt model was used to estimate elasticity and viscosity from the stress-strain response of the tissue. The authors reported average elasticity of 1.3 × 10^-3 N/mm and average viscosity of 89.33 × 10^-6 Ns/mm^2 across samples. Regionally, the lower bladder region showed the highest elastic response, while the upper region showed the highest viscous response under the isotropic conditions evaluated. The work establishes a combined digital and mechanical framework for representing bladder surface geometry together with regional tissue mechanics as a basis for future computational simulation of urinary bladder behaviour.

CELLSCALE INSTRUMENT USED

UniVert

Mechanical characterization of bovine urinary bladder tissue was performed using a CellScale UniVert stress machine. The bladder was divided into upper, middle, and lower regions, and a 3D-printed template was used to dissect standardized tensile specimens measuring approximately 150 mm^2 with a grip zone of 352.5 mm^2. Tensile testing was performed with a 200 N load and data acquisition at 1 ms intervals. The resulting stress-strain data were processed in Excel and MATLAB, and a linear viscoelastic Voigt model was fitted to identify elastic and viscous parameters for each tissue region. The UniVert measurements enabled the authors to compare mechanical differences across bladder regions and showed that the lower region was the most elastic while the upper region was the most viscous under the experimental conditions used.
AUTHORS

Keith Guzman-Diaz, Aurora Alvarado-Gonzalez, Daniela Herrera, Ana Hernandez-Reynoso, Sergio Rodríguez-Reynoso, Alejandro Garcia-Gonzalez.

PUBLICATION DETAILS
JOURNAL

IFMBE Proceedings

YEAR

2020

INSTITUTIONS

Tecnologico de Monterrey, University of Texas at Dallas

COUNTRIES

Mexico, United States

INSTRUMENT USED

UniVert

TESTING METHODS

Tensile Testing

RESEARCH APPLICATIONS

Gastrointestinal and Urinary Tract Biomechanics

Related Publications:

Instrument Used:
Year:
Testing Method:
Research Application:
Country:

A Thermoresponsive, Electrically Conductive Bioink Optimized for Electroactive Tissue Engineering and Bioelectronics

Byrne R, Redmond J, et al.

ACS Applied Bio Materials

UniVert

Compression TestingHydrated and Temperature Controlled TestingViscoelastic & Time-Dependent Testing

3D Bioprinting & Bioink Materials TestingElectroactive and Photothermal PolymersWearable Bioelectronics

2026

Depth-resolved phase velocity estimation in layered tissue based on an efficient additive attention network with surface acoustic wave – optical coherence elastography

Zhang G, Liao J, et al.

Biomedical Optics Express

UniVert

Compression Testing

Skin and Wound Healing Biomechanics

2026

Co-delivery of Human Adipose-Derived Stromal Cells and Endothelial Colony-Forming Cells in Cell-Assembled Decellularized Adipose Tissue Scaffolds for Applications in Soft Tissue Regeneration

From SA, Walker JT, et al.

Acta Biomaterialia

UniVert

Compression TestingMicro-Mechanical TestingUltra Low Force Testing

Cell Laden HydrogelsECM & Decellularized Matrix MechanicsInjectable & Regenerative BiomaterialsScaffold Mechanical TestingSkin and Wound Healing BiomechanicsVascular Tissue Engineering & Mechanics

2026

Contact Sales

Product of Interest: