PEER-REVIEWED PUBLICATION

2025

On-scalp printing of personalized electroencephalography e-tattoos

Vasconcelos LS, Yan Y, et al.

Cell Biomaterials

The University of Texas at Austin, University of California – Los Angeles

RESEARCH SUMMARY
This study introduces a full-head, on-scalp microjet printing technology for creating ultrathin, stretchable, self-drying EEG e-tattoos capable of high-fidelity electrophysiological monitoring on hairy scalps. The authors developed two biocompatible PEDOT:PSS-based inks—one optimized for low-impedance electrodes and one for high-conductivity interconnects—and paired them with a 5-axis robotic printing system guided by 3D head scans and a project-and-slice layout algorithm. Compared with conventional wet-gel EEG electrodes, the printed e-tattoos exhibited significantly lower and more stable contact impedance (<40 kΩ over 6 hours), superior skin conformability, strong mechanical adhesion, and robustness during motion. Performance was validated across multiple EEG modalities, including motor imagery and error-related potentials, demonstrating parity with gel electrodes while enabling long-term, comfortable, cap-free EEG acquisition.

CELLSCALE INSTRUMENT USED

UStretch

The CellScale UStretch mechanical testing system was used to perform peel-force measurements on porcine skin to compare adhesion between printed-on-skin films and transferred films. These quantitative peel tests demonstrated that directly printed PEDOT:PSS electrode and interconnect films adhered more strongly to biological tissue, supporting the device’s improved on-skin mechanical stability reported in the study.
AUTHORS

Luize Scalco de Vasconcelos, Yichen Yan, Pukar Maharjan, Satyam Kumar, Minsu Zhang, Bowen Yao, Hongbian Li, Sidi Duan, Eric Li, Eric Williams, Sandhya Tiku, Pablo Vidal, R. Sergio Solorzano-Vargas, Wen Hong, Yingjie Du, Zixiao Liu, Fumiaki Iwane, Charles Block, Andrew T. Repetski, Philip Tan, Pulin Wang, Martín G. Martín, José del R. Millán, Ximin He, Nanshu Lu.

PUBLICATION DETAILS
JOURNAL

Cell Biomaterials

YEAR

2025

INSTITUTIONS

The University of Texas at Austin, University of California – Los Angeles

COUNTRIES

United States

INSTRUMENT USED

UStretch

TESTING METHODS

Peel Testing

RESEARCH APPLICATIONS

Adhesives and Sealants TestingPolymers and Elastomers TestingWearable Bioelectronics

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On-scalp printing of personalized electroencephalography e-tattoos

Vasconcelos LS, Yan Y, et al.

Cell Biomaterials

UStretch

Peel Testing

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2025

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Adhesive Nonfibrotic Bioelectronic Interfaces on Diverse Peripheral Nerves for Long-Term Functional Neuromodulation

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Science Advances

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Fatigue TestingTensile Testing

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