Effects of Longitudinal Pre-stretch on the Mechanics of Human Aorta Before and After Thoracic Endovascular Aortic Repair (TEVAR) in Trauma Patients

This study investigated how longitudinal pre-stretch influences the biaxial mechanical behavior of human thoracic aortic tissue before and after thoracic endovascular aortic repair (TEVAR) in trauma patients. Native and post-TEVAR aortic samples were subjected to controlled biaxial loading to quantify changes in stiffness, anisotropy, and load sharing between circumferential and longitudinal directions. The results demonstrated that longitudinal pre-stretch significantly alters aortic mechanical response and that TEVAR implantation modifies native tissue mechanics, with important implications for vascular remodeling, graft–tissue interaction, and long-term device performance.