Viscoelastic Testing and Time Dependent Mechanics
of Soft Materials

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Viscoelastic testing characterizes how soft tissues, hydrogels, and biomaterials respond to time-dependent deformation, revealing important properties such as creep, stress relaxation, and recovery behaviour. As a result, viscoelastic testing is a core method in time dependent mechanical testing of biological and soft engineered materials.

A closeup of a tensile test on the UniVert in a horizontal media bath for creep testing
UniVert Data Analysis software with UniVert viscoelastic testing data, image, and graphs
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What Viscoelastic Testing Measures

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Viscoelastic testing provides critical insight into mechanical behaviour not captured by standard stiffness or strength measurements.

Because biological materials often exhibit both fluid-like and elastic responses, viscoelastic testing is essential for understanding mechanical function in physiologic and engineered environments.

These responses reveal how materials dissipate energy, redistribute internal stresses, and deform under sustained loading. Together, these measurements form the basis of quantitative viscoelastic characterization for soft tissues and biomaterials.

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Viscoelastic Testing in Biomaterials Research

Soft tissues and biomaterials frequently experience long duration or cyclic loading in vivo. Viscoelastic characterization helps researchers understand:

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Common Sample Types for Viscoelastic Testing

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How a Viscoelastic Test Works

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Viscoelastic testing uses controlled protocols that examine how a material responds over time. Common protocols include stress relaxation testing and creep testing, which isolate complementary aspects of time-dependent mechanical behaviour.

A constant deformation is applied and the decay in force is measured over time. This reveals how internal stresses dissipate in soft materials.

A constant force is applied and the resulting increase in deformation is recorded. Useful for characterizing long term load bearing performance.

Applying deformation at different speeds uncovers how materials stiffen or soften with strain rate.

Repeated loading assesses hysteresis, energy dissipation and fatigue like behaviour.

CellScale chambers support physiologic temperature and hydration to maintain time dependent mechanics representative of biological conditions.

Recommended CellScale Instruments for Viscoelastic Testing

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Many CellScale systems support viscoelastic testing through precise force and displacement control for creep, stress relaxation, and time-dependent mechanical analysis.

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Publications Using Viscoelastic Testing

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FGF-2 signaling dominance in TGF-β1/FGF-2–primed nasoseptal chondrocytes for cartilage tissue engineering

Ma Z, Grimes K, et al.

Journal of Tissue Engineering

MicroTester

Compression TestingMicro-Mechanical TestingStress Relaxation TestingViscoelastic & Time-Dependent Testing

Cartilage and Meniscus MechanicsMicrotissue and Spheroid Mechanics

2026

Passive biaxial mechanics and viscoelastic relaxation of the thoracic aorta in intermittent hypobaric hypoxia

Álvarez-Carrasco F, Brito E, Navarrete Á, et al.

Extreme Mechanics Letters

BioTester

Biaxial TestingDigital Image Correlation (DIC)Hydrated and Temperature Controlled TestingStress Relaxation TestingViscoelastic & Time-Dependent Testing

Vascular Tissue Engineering & Mechanics

2026

Oxygen Consumption Rate-Defined Phases Couple Metabolism to Matrix Dynamics in Chondrocyte-Mesenchymal Stromal Cell Co-Culture

Ma Z, McEachern L, et al.

The FASEB Journal

MicroTester

Compression TestingMicro-Mechanical TestingStress Relaxation TestingViscoelastic & Time-Dependent Testing

Cartilage and Meniscus MechanicsMicrotissue and Spheroid MechanicsStem Cell Mechanobiology

2026

Ready to Perform Viscoelastic Testing?

CellScale instruments provide precise control for viscoelastic characterization of soft materials, tissues, and micro-scale constructs.

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