CellScale BlogWelcome to our blog page! This is split into different series of stories. Check out the In the Lab series where we catch up with researchers using CellScale systems. Caleb's Corner is where our president pens his insights on the industry. Finally the Product Launch series introduces the latest in CellScale R&D. Enjoy browsing!
Ludovica Cacopardo from the University of Pisa under Associate Professor Arti Ahluwalia publishes this article on a new testing method for viscoelasticity through stress-rate measurements and load-control testing. Learn how the MechanoCulture TR played a major role in their discovery.
Here is the first customer publication highlight featuring a commercial (non-academic) entity and their research with our equipment! Dr. Desmond Adler and his team from Avedro (now a Glaukos company) investigated on the optimization of oxygen dynamics, UV-A delivery, and drug formulation for Accelerated Epi-On Corneal Crosslinking.
University of Arizona’s Dr. Jeong-Yeol Yoon and his Ph.D. student Kattika Kaarj presents this journal paper on Organ-on-a-chip devices and the mechanical stimuli they can create on human cells and tissues. This excellent summary focuses on the technical details of device design and equipment used, categorizing them under 5 types of mechanical stimuli.
CellScale User Publication Highlight: Effects of Different Constitutive Laws on Fluid-Structure Interaction (FSI) Simulation of the Mitral Valve
Dr. Xiaoyu Luo from the University of Glasgow in collaboration with 3 top scientific universities in China has presented a highly detailed study on the dynamic behavior of mitral valve leaflets and chordae tendineae under physiological conditions.
CellScale User Publication Highlight: Nb2O5 and HA Particle Loaded Electrospun PCL/GL Membranes for Bone Tissue Engineering
Dr. Kathryn Grandfield and her team from McMaster University in collaboration with Federal University of Pelotas designed and fabricated membranes with the ideal bone quality and bioactivity favoured in bone repair applications. Learn more about their methods and test results.
CellScale User Publication Highlight: Surface Representation and Bio-mechanical Analysis of the Urinary Bladder
Dr. Alejandro Garcia-Gonzalez from Tecnologico de Monterrey in collaboration with the University of Texas at Dallas presents this paper that characterizes the urinary bladder in research to benefit the treatment of stress urinary incontinence.
CellScale User Publication Highlight: Regional-Dependent Biaxial Behavior of Young and Aged Mouse Skin
Dr. Manuel Rausch and his team at the University of Texas at Austin published this comprehensive study on the detailed histomechanical characterization, residual strain
analysis, and constitutive mode of murine skin.
CellScale presents the latest innovation in microphysiological systems.
Dr. Diane Gregory and Maxine Harvey-Burgess from Wilfrid Laurier University published this article in Spine Biomechanics journal that studied the effect of axial torsion on the mechanical properties of the annulus fibrosus inter- and intralamellar matrices.
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CellScale User Publication Highlight: Compressive Mechanical Properties of Rat and Pig Optic Nerve Head
Dr. Ross Ethier and his team from Georgia Institute of Technology furthered the research on Glaucoma through biomechanical studies on the optic nerve head tissue of a rat and pig.
CellScale User Publication Highlight: Effect of Halloysite Addition on the Material Properties of Chitosan-Halloysite Hydrogel Composites
Chitosan is an exceptional candidate for implant coatings, wound dressing, and drug delivery applications. However, it has poor mechanical properties on its own and often needs to be reinforced with other polymers, carbon nanotubes or clay nanoparticles. Dr. David Mills and Yangyang Luo from Louisiana Tech University explores the addition of Halloysite in Chitosan, studying the material properties as well as its drug delivery capabilities.
CellScale User Publication Highlight: 3D Bioprinting with Methacrylated Gelatin Upon Inclusion of Chroride Salt and Nano-Particles
Dr. Patricia Comeau and Dr. Thomas Willett from the University of Waterloo optimizes a methacrylated gelatin-based bioink with chloride salt and hydroxyapatite nano-particles. In their experiments, they optimized for viscosity, swelling and dynamic modulus. Their printed result possessed a dynamic modulus similar to articular cartilage.
CellScale Collections: Publications from Dr. Alexey Kamenskiy from the University of Nebraska Omaha featuring the BioTester.
CellScale User Publication Highlight: A Comparison Between Thin Films and Inverse Double Network Bilayers for Oral Drug Delivery Systems
Dr. Teja Guda and his team from the Department of Biomedical Engineering at the University of Texas at San Antonio assessed the inverse double network (IDN) hydrogel setup for use in oral drug delivery applications.
Have you invented a new product in your lab that you can’t wait to take to the market? Before you put 2 feet into the water (in this case, the ocean), have a read at what Caleb Horst has to say from over 15 years of experience launching new products.
CellScale User Publication Highlight: A Bioink Blend for Rotary 3D Bioprinting of Vascular Constructs
Dr. Kaiming Ye and his team at Binghamton University and Syracuse University successfully developed a rotary 3D bioprinter and a fibrinogen/gelatin-based bioink. They printed customized vessel grafts that could produce a burst pressure about 52% that of the human saphenous vein.
CellScale User Publication Highlight: Prediction of Hyperelastic Material Properties of Fuel Cell Membranes
In the automotive industry, the use of fuel cells is gaining popularity, so thus the understanding of the mechanical properties of the membranes in those fuel cells. Dr. Nemavhola and Dr. Sigwadi from the University of South Africa presents to us a systematic and analytical study of various material models on 2 types of membranes.