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Mechanical Test Systems

At CellScale, our test systems are optimized from the ground up to characterize the mechanical properties of biomaterials. Environmental chambers and imaging are integral system functions, not afterthoughts. For needs ranging from micro-scale compression to biaxial tension, trust CellScale’s systems to provide cutting edge data. Our products are:

BioTester – planar biaxial testing

MicroTester – micro-scale mechanical testing

UniVert – tension, compression and bending testing

UStretch – precision tension testing


CellScale’s bioreactors provide insights into the response of cells and tissues to mechanical stimulation.  We have systems optimized for high-throughput, real-time imaging, 3D scaffold use, and multi-modal stimulation. CellScale also has extensive experience in developing custom solutions that exceed expectations. The Cell-Stimulation products are:

MCB1  – biaxial stimulation of cell monolayers and 3D constructs

MCFX – uniaxial stimulation of cell monolayers with imaging

MCT6 – high-force uniaxial stimulation of 3D constructs

MCTR – high-throughput hydrostatic pressure stimulation

MCTX – uniaxial compression stimulation

We have bought multiple CellScale products and are extremely happy with all of them.  The BioTester is by far the best-designed, easiest-to-use biaxial testing system I have used in my career. The MechanoCulture B1 provides great control over mechanical stretch protocols and is the only system we have found that readily accommodates cell-populated gels. Finally, the MechanoCulture FX is a great system for mechanobiology experiments. Across all of these products, CellScale has worked with us to help us find the right product, and when needed even to adapt their devices for our experiments. I can’t recommend the products and the company highly enough. Prof. Jeff Holmes

University of Virginia

CellScale’s innovative biomechanical testing equipment, including the MicroTester and a customized UniVert system, has greatly enabled our research, allowing us to accurately characterize the properties of a diverse range of engineered bioscaffolds under physiological conditions. The systems are robust and easy to use, and offer flexibility in the types of biomaterials and tissues that can be tested. What truly sets CellScale apart, is their commitment to Customer Service – they have gone above and beyond to help us in getting the most from our data and are always very prompt and helpful in responding to our questions.

Lauren Flynn, Ph.D., P.Eng
Western University

CellScale User Publication Highlight: 3D Bioprinting with Methacrylated Gelatin Upon Inclusion of Chroride Salt and Nano-Particles

Dr. Patricia Comeau and Dr. Thomas Willett from the University of Waterloo optimizes a methacrylated gelatin-based bioink with chloride salt and hydroxyapatite nano-particles. In their experiments, they optimized for viscosity, swelling and dynamic modulus. Their printed result possessed a dynamic modulus similar to articular cartilage.

Collections: Alexey Kamenskiy

CellScale Collections: Publications from Dr. Alexey Kamenskiy from the University of Nebraska Omaha featuring the BioTester.

CellScale User Publication Highlight: A Comparison Between Thin Films and Inverse Double Network Bilayers for Oral Drug Delivery Systems

Dr. Teja Guda and his team from the Department of Biomedical Engineering at the University of Texas at San Antonio assessed the inverse double network (IDN) hydrogel setup for use in oral drug delivery applications.

Time to Start Selling?

Have you invented a new product in your lab that you can’t wait to take to the market? Before you put 2 feet into the water (in this case, the ocean), have a read at what Caleb Horst has to say from over 15 years of experience launching new products.

CellScale User Publication Highlight: A Bioink Blend for Rotary 3D Bioprinting of Vascular Constructs

Dr. Kaiming Ye and his team at Binghamton University and Syracuse University successfully developed a rotary 3D bioprinter and a fibrinogen/gelatin-based bioink. They printed customized vessel grafts that could produce a burst pressure about 52% that of the human saphenous vein.

CellScale User Publication Highlight: Prediction of Hyperelastic Material Properties of Fuel Cell Membranes

In the automotive industry, the use of fuel cells is gaining popularity, so thus the understanding of the mechanical properties of the membranes in those fuel cells. Dr. Nemavhola and Dr. Sigwadi from the University of South Africa presents to us a systematic and analytical study of various material models on 2 types of membranes.

CellScale User Publication Highlight: Multifactorial Bottom-up Bioengineering Approaches to Develop Living Tissue Substitutes

Dr. Dimitrios Zeugolis is a biomedical engineering lecturer at the National University of Ireland-Galway. He established the Regenerative, Modular & Developmental Engineering Laboratory (REMODEL) and is a Principal Investigator at the Science Foundation Ireland (SFI) Centre for Research in Medical Devices (CÚRAM) at NUI Galway. Along with co-founding a company – Vornia Biomaterials Ltd, Dr. Zeugolis is part of the editorial committee of TERMIS. CellScale is honoured to feature an article done by Dr. Zeugolis and his team in a research that used our product – the MechanoCulture T6.

CellScale User Publication Highlight: Investigating the Venous Valve Tissue Mechanical Properties and ECM

Dr. Hsiao-Ying Shadow Huang from North Carolina State University made great advances in this paper. Utilizing the BioTester, SEM and light microscope, Dr. Huang and her team were able to characterize bovine jugular venous valve tissue for their biaxial mechanical properties and tissue microstructure.

CellScale User Publication Highlight: Molecularly-ordered Hydrogels with Controllable Response

In this research from Dr Taylor Ware and his team at the University of Texas at Dallas, small hydrogels of chromonic properties morph into programmed shapes in response to pH and temperature stimuli.

CellScale Attends ASEE2019 with the UniVert Classroom

CellScale attends ASEE2019 in Tampa, Florida on June 15-19! We will be showcasing the UniVert Classroom – the ultimate learning kit that teaches about mechanical properties of biomaterials.